Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study1
نویسندگان
چکیده
Background: Evidence on the effects of lifestyle interventions on plasma fatty acid composition in children is limited. Objective: We investigated the effects of a dietary and physical activity intervention on plasma fatty acid composition of cholesteryl esters (CEs) and phospholipids and estimated desaturase and elongase activities in children. Design:We conducted a 2-y controlled dietary and physical activity intervention based on Finnish nutrition and physical activity recommendations in a population sample of 506 children aged 6–8 y. We assessed plasma fatty acid composition by gas chromatography and estimated desaturase and elongase activities as the ratio of product fatty acids to precursor fatty acids. We analyzed data by using linear mixed models adjusted for age and sex. Results: The proportion of total polyunsaturated fatty acids (PUFAs) in CEs tended to increase in the intervention group compared with the control group (P = 0.007 for group 3 time interaction). The proportion of total PUFAs in phospholipids (P = 0.019 for group 3 time interaction) and the proportion of linoleic acid in CEs (P = 0.038 for group 3 time interaction) decreased in the control group. The proportion of a-linolenic acid in CEs (P , 0.001 for group 3 time interaction) increased and in phospholipids (P = 0.015 for group 3 time interaction) tended to increase in the intervention group. The proportion of stearic acid in CEs decreased in the intervention group (P = 0.001 for group 3 time interaction). The proportion of oleic acid in CEs (P = 0.002 for group 3 time interaction) increased and in phospholipids (P = 0.023 for group 3 time interaction) tended to increase in the control group. Estimated elongase activity in CEs decreased in the control group (P = 0.050 for group 3 time interaction). Intervention had no effect on estimated desaturase activities. Conclusions: Dietary and physical activity intervention had a beneficial effect on plasma fatty acid composition in children by preventing the decrease in the proportion of total PUFAs and linoleic acid and by increasing the proportion of a-linolenic acid. This study was registered at clinicaltrials.gov as NCT01803776. Am J Clin Nutr doi: 10.3945/ajcn.116.136580.
منابع مشابه
The Effect of Dietary Approaches to Stop Hypertension on Weight, Body Composition, and Blood Pressure of Children with Attention Deficit Hyperactivity Disorder: A Randomized Controlled Clinical Trial
Background: Attention deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children. Children with ADHD usually have low blood pressure and weight disorders. Therefore, the present randomized clinical trial was conducted to evaluate the effect of Dietary Approaches to Stop Hypertension (DASH) on weight and blood pressure of children with ADHD. Methods: In ...
متن کاملMothers’ Self-Efficacy Regarding Dietary Behaviour and Physical Activity of Preschool Children
Background Obesity constitutes a crucial health issue during preschool period and has an impact on children regardless their ethnic backgrounds. The purpose of the study was to examine the self-efficacy perceptions of mothers and potential differences and correlations with dietary behaviour and physical activity of their preschool children in Finland. Materials and Methods: The sample for this...
متن کاملFamilial Resemblance of Body Composition, Physical Activity, and Resting Metabolic Rate in Pre-School Children
Background: Although parental obesity is a well-established predisposing factor for the development of obesity, associations between regional body compositions, resting metabolic rates (RMR), and physical activity (PA) of parents and their pre-school children remain unknown. The objective of this study was to investigate parent-child correlations for total and regional body compositions, restin...
متن کاملComparison of Physical Activity and Fiber and Sugar Intake in Patients with Nonalcoholic Fatty Liver Disease with Healthy Individuals
Introduction: Nutrition as a modifiable risk factor that plays an important role in prevent or delay the onset of non-alcoholic fatty liver disease (NAFLD). Thus, the aim of the current study was to assess and compare physical activity, dietary fiber and sugar intake between non-alcoholic fatty liver disease and healthy individuals.Methods: The present case-con...
متن کاملEffect of health promotion program with collaborative approach on physical activity of overweight school-age girls
Background: Nowadays, due to ineffectiveness of interventions in the prevention of obesity in school-age children, collaborative approach in order to prevent and control the obesity seems necessary. Aim: to assess the impact of health promotion programs with collaborative approach on physical activity levels of overweight school-age girls. Methods: This quasi-experimental and pretest/post-test ...
متن کامل